We work on poliovirus cell entry, investigating the molecular
mechanism of infection using electron microscopy and other biophysical
We also look at poliovirus in complex with antibodies to trap
We are investigating Seneca Valley Virus and its role in cancer
therapy as an oncolytic virus.
We are looking at electrically conductive filaments, how they
transport electricity, and how they can be used in microbial fuel
Cellular receptors, like the insulin receptor, are important
molecules in cell signalling and metabolism. Our structural analysis
of these membrane proteins helps explain how they function and unlocks
potential therapies for treatment.