Poliovirus Cell Entry
Finding the molecular mechanism of infection
We use poliovirus as a model for picornavirus infection to study the infection pathway by cryoEM.
Active Projects
Finding the molecular mechanism of infection
We use poliovirus as a model for picornavirus infection to study the infection pathway by cryoEM.
Finding the molecular mechanism of infection
Complexes with antibodies can trap intermediates in the infection pathway by cryoEM.
Electrically conductive filaments
We are examining the structure of specialised extensions of bacteria that can conduct electricity.
Pursuing oncolytic viral therapeutics
This interesting virus is in clinical trials for treatment of specific cancers. We want to investigate the mechanism of infection.
Structure and mechanisms of fully liganded Insulin Receptor
Biophysical and structural analysis of membrane proteins can help explain their physiological function and help explain mechanisms of disease.
Ultrastructure of undocumented species
Structural biology can help classify and make sense of genomic information when categorising newly discovered strains or species.
Granting Agencies
Generous Support from Donors
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